Geeky Science!! Fat Loss Explained

Lypolysis is the process by which triglycerides are hydrolyzed into free fatty acids and follow a path of degradation into acetyl units via beta-oxidation.

Through the release of epinephrine, norepinephrine, ghrelin, growth hormone, testosterone and cortisol, we trigger the activation of 7 TM receptors.

Through the activation of 7 TM receptors the following catalyst begins.

7TM-adenylate cyclase-Cyclic adenosine monophosphate-protein kinase A.

Once protein kinase A has been activated lipases found in adipose tissue will start to breakdown triglyceride structure into available free fatty acids.

Once free fatty acids are available hepatic glycerol 3-phosphate is converted into dihydroxyacetone phosphate which ends in available acetyl units required for energy metabolism.

lt is very important to note that vitamin B3 is the major contributing factor in the beta-oxidation of dihydroxyacetone phosphate into usable acetyl units therefore if this vitamin is deficient in dietary intake the metabolism of fats for fuel will be hampered.

As a rule when undergoing a low carbohydrate diet the rate of beta-oxidation increases dramatically and as such you will need to supplement B vitamins to ensure amino acid transamination as well as mediated energy metabolism.

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